Thyroid Gland and Disorders

Thyroid Gland and Disorders

Introduction

The thyroid gland plays a vital role in metabolism, energy regulation, and growth. Understanding thyroid hormone physiology is crucial for diagnosing conditions like hypothyroidism and hyperthyroidism.

Thyroid Hormones & Their Functions

  • T3 (Triiodothyronine) – Active form of thyroid hormone, increases metabolism.
  • T4 (Thyroxine) – Precursor to T3, maintains metabolic stability.
  • Calcitonin – Regulates calcium homeostasis.

Thyroid Disorders

  1. Hypothyroidism

    • Causes: Iodine deficiency, Hashimoto’s thyroiditis.
    • Symptoms: Fatigue, weight gain, bradycardia, cold intolerance.
    • Treatment: Levothyroxine (T4 replacement therapy).
  2. Hyperthyroidism

    • Causes: Grave’s disease, toxic multinodular goiter.
    • Symptoms: Weight loss, tachycardia, heat intolerance, exophthalmos.
    • Treatment: Antithyroid drugs (Methimazole, Propylthiouracil), radioactive iodine therapy.
  3. Thyroid Neoplasms

    • Types: Papillary, follicular, medullary, and anaplastic thyroid cancer.

Conclusion

Thyroid disorders are among the most common endocrine diseases. These MBBS notes provide an in-depth guide for diagnosis and treatment strategies.

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