Adrenal Glands ; Their Role in Stress Response

Adrenal Glands ; Their Role in Stress Response

Introduction

The adrenal glands regulate stress, metabolism, and electrolyte balance through hormones like cortisol, aldosterone, and adrenaline.

Adrenal Cortex Hormones

  1. Glucocorticoids (Cortisol) – Regulates metabolism, immune response, and stress adaptation.
  2. Mineralocorticoids (Aldosterone) – Controls sodium and potassium balance.
  3. Androgens (DHEA, Testosterone) – Supports secondary sexual characteristics.

Adrenal Disorders

  1. Cushing’s Syndrome (Excess Cortisol)

    • Symptoms: Moon face, buffalo hump, hyperglycemia, hypertension.
    • Causes: Prolonged steroid use, adrenal tumors, pituitary adenomas.
  2. Addison’s Disease (Cortisol Deficiency)

    • Symptoms: Fatigue, weight loss, hypotension, hyperpigmentation.
    • Treatment: Corticosteroid replacement therapy.
  3. Pheochromocytoma

    • A rare adrenal tumor causing hypertension, palpitations, and excessive sweating.

Conclusion

Adrenal gland disorders require early diagnosis and intervention. These MBBS notes offer a structured approach to understanding adrenal physiology and pathology.

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